PET HEALTH · 21-PET APPROVED
Frontline Spray Flea, Tick & Lice Treatment
★★★★★ Tested across our 18-dog household · Including Thunder · Power Paw
“With 18 dogs, flea and tick control isn’t optional. This spray is what we actually keep at home.”
A trusted flea, tick and lice treatment spray for dogs and cats, formulated with Fipronil 0.25%. Applied to the full coat, it kills fleas within 24 hours, ticks within 48 hours, and eliminates chewing lice — while remaining effective for up to 30 days. Safe for use on puppies and kittens from 2 days of age. 250ml per bottle.
OUR HONEST TAKE
- Best for: Multi-pet households or any home dealing with an active flea or tick infestation — this is what we use with 21 Paws
- Effective and proven: Kills up to 100% of existing fleas in less than 24 hours, continues working for a month or more, and remains effective even if your pet swims or is bathed
- Important: Wear latex gloves when applying. For head and eye area, spray onto your gloved hand first — do not spray directly on face. Always follow the label directions
- Kills fleas within 24 hours, ticks within 48 hours, and chewing lice on contact
- Waterproof protection for up to 30 days — effective even after swimming or bathing
- Full-coat spray application ensures every part of the coat is covered — not just one spot
WHY WE PICKED THIS
In a house with 18 dogs, flea season is serious business
We don’t take pest prevention lightly. With 18 dogs living together, if one comes home with fleas, everyone gets them — fast. We’ve tried a lot of sprays and spot treatments over the years, and Frontline has been the one we keep coming back to.
What we like most is how it works: you spray the full coat rather than just one spot, which means coverage is immediate across the whole body. Thunder gets treated along with everyone else — and with a thick coat, the spray format works better than a spot-on applicator for making sure everything actually gets covered.
A month’s protection per application, and it holds even after baths — that matters when you have dogs that run through everything outside.
What's in the bottle
Active Ingredient
Fipronil 0.25%
Volume
250ml per bottle
Suitable For
Dogs, cats, puppies and kittens from 2 days of age
Protection Duration
Up to 30 days per application
Thunder
Power Paw
“With a household this size, we can’t afford for flea control to fail. We’ve used Frontline for Thunder and the rest of the pack — the full-coat spray format makes sure nothing gets missed, especially with her thick double coat.”
Used as part of regular monthly prevention routine
Q: How much should I use?
For the 250ml bottle, approximately 1–2 pumps per pound of body weight. The coat should be damp to thoroughly wet after application — this ensures full coverage and effectiveness.
Q: Is it safe for puppies and kittens?
Yes — Frontline Spray is safe for use on puppies and kittens from 2 days of age. Always follow the label instructions and consult your vet if you have concerns about young or small animals.
Q: When can my pet get wet after application?
The spray is waterproof and remains effective even after swimming or bathing. However, we recommend waiting at least 48 hours after application before your pet gets wet for the first time, to allow the product to fully absorb into the skin oils.
Q: Can it be used on cats?
Yes — this spray formula is approved for both dogs and cats. It is different from some Frontline spot-on products that are dog-only, so the spray is a good option for multi-pet households with both cats and dogs.
Complete the pet health routine
Pet Ear Cleaner Wipes for Dogs & Cats
Pre-moistened round cotton pads designed for quick, gentle ear cleaning.
Pet Ear Mite Treatment Drop for Dogs & Cats
A gentle but effective ear mite treatment formulated with natural tea tree oil and eucalyptus oil.
See how we apply it across our 21 paws
Watch the full application routine — then shop directly on TikTok, where TikTok’s buyer protection covers your order.